Myeloid Clusters

Gene Expression

CD14+ Monocytes

FCGR3A+ Monocytes

Macrophages

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## following requested variables were not found: rna_ADREG1

Mast cells

Megakaryocytes/ Platelets

conventional dendritic cells (cDCs)

plasmacytoid dendritic cells (cDCs)

Proinflamatory

Anti-inflammatory

Clusters’ Gene Markers

Cluster 0

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
APOE 2.88278192098325 0.947 0.418 0
CCL18 2.23345210079847 0.458 0.122 0
APOC1 2.03019460375418 0.887 0.365 0
NUPR1 1.70021771728917 0.677 0.168 0
CTSD 1.64316897087188 0.989 0.726 0
RNASE1 1.50514343015995 0.784 0.324 0
TREM2 1.49944598074128 0.71 0.182 0
GPNMB 1.43911197653819 0.872 0.366 0
CTSL 1.33240429877123 0.884 0.505 0
C1QB 1.32681506392809 0.957 0.511 0
C1QC 1.32284488853637 0.956 0.492 0
CTSB 1.29663545093147 0.976 0.809 0
PLD3 1.2448917204248 0.843 0.407 0
FCGR3A 1.24318809557217 0.772 0.381 0
C1QA 1.23272162056861 0.965 0.55 0
SPP1 1.52191860732787 0.604 0.236 9.46247911283734e-284
CCL13 1.39990391504156 0.301 0.066 7.83451570876089e-272
IFI27 1.98122870240428 0.563 0.249 2.65687797315837e-235
IFI6 1.37824299869229 0.708 0.393 1.24758267296451e-207
CCL2 1.2277195526477 0.453 0.212 1.64023869144124e-139

Cluster 1

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
EREG 1.86616835063278 0.656 0.263 0
FCN1 1.16309883906414 0.478 0.166 6.45544741221081e-221
NAMPT 1.11329401706873 0.842 0.635 3.21781095152592e-189
IL1B 1.12478961881595 0.829 0.532 3.64122135645172e-187
THBS1 1.44827431324277 0.424 0.172 5.86258853060687e-166
BTG1 1.03522737847816 0.893 0.772 1.02416574625996e-163
IL1RN 1.45187936000306 0.583 0.311 1.08101095455305e-159
TIMP1 1.41139375659591 0.873 0.746 5.21975665948205e-153
SOD2 1.15418467956226 0.877 0.7 2.64798552141318e-133
G0S2 1.4593497259647 0.606 0.371 4.72349917679473e-124
AQP9 0.944174542542593 0.367 0.178 2.35844073779029e-92
BCL2A1 1.01955800551444 0.684 0.507 3.72314845778493e-86
OLR1 0.937393121749452 0.47 0.281 1.0474436299591e-81
PPIF 1.11712569857457 0.534 0.369 5.21114982342679e-81
ATP2B1 0.872538254782854 0.524 0.356 6.52490987534515e-81
C15orf48 1.15489261245539 0.685 0.538 6.47860142229022e-71
CXCL8 1.39187555373343 0.661 0.511 2.33362342442946e-68
AREG 0.999085993319599 0.444 0.298 2.42580624808755e-46
CCL20 1.00269700532262 0.403 0.261 1.32686889421959e-43
HCAR3 1.09057161967179 0.107 0.053 8.75533328865399e-18

Cluster 2

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
APOC1 2.46246631931324 0.898 0.384 0
GPNMB 1.46009323749543 0.812 0.391 0
FTL 1.27972959139943 1 0.999 0
CTSD 1.2720041900856 0.959 0.738 0
APOE 1.22733665649251 0.896 0.443 0
CSTB 1.29405388537814 0.94 0.799 2.15255852693872e-239
CTSB 0.816573507107234 0.934 0.819 3.13416558382497e-153
OTOA 0.905429138191621 0.381 0.138 2.40133219428503e-151
LIPA 1.24146255552223 0.67 0.412 1.80532922242854e-150
ACP5 1.00579834623901 0.777 0.49 2.00486227580233e-147
FABP5 1.55239802799443 0.689 0.457 7.16022865693894e-136
LGALS3 0.922583588720338 0.877 0.704 4.08209361255099e-130
SPP1 1.7354357309838 0.516 0.259 6.72857862215602e-126
GCHFR 1.0872377317177 0.396 0.181 8.33691048013621e-109
NUPR1 1.63286291741608 0.434 0.211 4.56491026118078e-95
FN1 1.17211572655079 0.271 0.124 7.10354370283951e-61
FBP1 0.957855857736247 0.353 0.231 8.5290769766092e-35
MT-RNR1 0.857292797908836 0.298 0.182 3.72596420048494e-31
MT-RNR2 0.91338781750555 0.307 0.198 2.42052633182016e-26

Cluster 3

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
C1QC 1.42802488179949 0.916 0.516 0
C1QB 1.40601858010393 0.923 0.533 0
C1QA 1.24923633972454 0.93 0.571 6.23550050719361e-301
MMP12 1.66509416490265 0.55 0.168 2.7373891568967e-284
DNASE1L3 1.78738380041416 0.533 0.182 4.74542874599818e-243
HLA-DPA1 1.00051116638408 0.987 0.841 1.75171909318046e-211
CD74 0.880496685703303 0.994 0.917 4.83629308150992e-203
HLA-DRA 0.863496741487656 0.995 0.919 3.33373547169769e-190
SLC40A1 1.07731228501814 0.657 0.288 6.43975723551719e-183
HLA-DQA1 0.984933347250038 0.952 0.719 4.70596028160717e-174
ADAMDEC1 0.905263758657201 0.463 0.165 8.33219076825629e-173
HLA-DMB 0.933549136113024 0.85 0.586 9.5572516253362e-169
TMEM176B 1.02679003942822 0.792 0.521 5.05918833557931e-163
ACP5 1.17503982781868 0.781 0.491 2.31405622365388e-155
HLA-DRB1 0.958428221173891 0.969 0.872 2.86952980100266e-140
S100B 0.855820080598856 0.339 0.109 2.35624276892088e-139
FUCA1 1.45784454287228 0.559 0.27 7.81365059414796e-136
SEPP1 1.12160669458277 0.641 0.328 7.0894279664644e-135
CTSC 0.890649924766302 0.839 0.633 1.80366042005192e-115
MMP9 1.10953133881309 0.493 0.236 2.12895960382631e-107

Cluster 4

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
FCER1A 2.64787713844971 0.636 0.099 0
CLEC10A 2.11852981798523 0.798 0.228 0
CD1C 2.00196506230139 0.583 0.039 0
CD1E 1.74608782849739 0.49 0.029 0
HLA-DQB1 1.62640237570068 0.991 0.741 0
HLA-DQA1 1.55739218566633 0.997 0.718 0
PPA1 1.53584503246054 0.789 0.372 0
HLA-DPB1 1.51567247721621 0.998 0.848 0
LGALS2 1.51034165113082 0.726 0.244 0
CST7 1.43090471162205 0.504 0.11 0
HLA-DPA1 1.3854740682816 0.997 0.842 0
PKIB 1.25969431342378 0.487 0.104 0
HLA-DRB1 1.27278096108596 0.994 0.871 5.35128170520374e-302
LSP1 1.3564169602646 0.892 0.479 4.29963482737856e-299
JAML 1.33411054734863 0.549 0.194 1.24821478159225e-236
CCL22 1.47119129324853 0.142 0.011 5.73249932836492e-221
CCL17 2.14108436711047 0.112 0.006 5.31534574688259e-219
CCR7 1.45765874072915 0.234 0.038 3.07319897069485e-204
HLA-DRB5 1.3016153070881 0.791 0.571 3.06760336195868e-123
HLA-DQA2 1.34874402137074 0.538 0.272 2.16430249811807e-109

Cluster 5

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
TPSAB1 8.26560729150682 0.991 0.014 0
TPSB2 8.02527802158418 0.7 0.027 0
CPA3 4.87922945041636 0.838 0.004 0
CTSG 4.55152488793254 0.536 0.004 0
CD69 4.13513620581259 0.798 0.161 0
HPGDS 3.78288879634168 0.836 0.057 0
HPGD 3.72853570499728 0.647 0.018 0
MS4A2 3.69040759601058 0.65 0.001 0
CLU 3.63037254934891 0.782 0.042 0
VWA5A 3.30699063518473 0.741 0.036 0
GATA2 3.21871615225677 0.7 0.002 0
LTC4S 2.96691612512363 0.736 0.1 0
KIT 2.78093416800526 0.585 0.003 0
SLC18A2 2.65575532519199 0.601 0.001 0
C1orf186 2.65059488855429 0.605 0.011 0
KRT1 2.50776858056244 0.403 0.001 0
ANXA1 2.49796650868062 0.933 0.709 0
RGS13 2.49696864390357 0.544 0.021 0
HDC 2.32091400912471 0.526 0.001 0
RP11-354E11.2 2.29108499516614 0.532 0.001 0

Cluster 6

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
F13A1 1.52393681254658 0.554 0.175 1.99401537712428e-247
FOLR2 1.37164426390631 0.586 0.208 8.97600814664865e-226
SEPP1 1.38033900505057 0.767 0.324 8.10451660103537e-225
FOS 1.38545473854711 0.954 0.779 2.84162582085849e-205
FOSB 1.16932092774959 0.912 0.693 9.90234027676878e-180
LYVE1 1.15724370068799 0.269 0.052 1.33220141351454e-178
EGR1 1.48067061102184 0.703 0.378 1.35923436092304e-166
STAB1 1.09867023582316 0.666 0.336 2.59263369773653e-150
MS4A7 1.09456075630614 0.827 0.587 1.70481672362038e-143
NR4A2 1.18339661437501 0.762 0.504 1.78210619785362e-135
MAF 1.13920736230218 0.535 0.265 1.88490127851273e-116
ATF3 1.08159111798587 0.629 0.379 3.03749022465631e-107
PLTP 1.18935667606912 0.493 0.236 1.94756905386569e-102
IER2 1.09828743448888 0.742 0.557 2.65092741917743e-98
SLC40A1 0.997574719256899 0.577 0.3 1.95342119272325e-93
SGK1 1.04027830953481 0.73 0.539 8.28737103041409e-89
KLF2 1.00565335799455 0.442 0.22 1.48611640746661e-82
CCL4 1.11901651590224 0.681 0.481 5.08764676672444e-66
PDK4 1.09697649837065 0.289 0.151 1.43948203344951e-39
CCL4L2 1.04856621864584 0.461 0.356 2.9763138706905e-20

Cluster 7

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
CCL3L3 3.12701094288061 0.781 0.349 0
CCL3 2.98626149741166 0.985 0.559 0
CCL4L2 2.75614440226155 0.769 0.334 0
CCL4 2.69676730850608 0.963 0.461 0
IL1B 2.1183504993894 0.942 0.535 0
CXCL2 2.18264443751329 0.849 0.47 4.83072018403911e-248
CXCL3 2.38228897459913 0.804 0.413 3.38178333688039e-239
CCL20 2.63779228797789 0.636 0.249 2.64806402393775e-235
SOD2 1.47543392601193 0.956 0.702 2.78393772031286e-230
PTGS2 2.03932510851807 0.711 0.32 5.40522958632062e-228
BCL2A1 1.6352679053655 0.845 0.502 2.544748876794e-216
CXCL8 2.07873596002315 0.794 0.508 4.50159488313208e-189
TNFAIP6 1.53908778813737 0.374 0.1 1.3033259444704e-178
INHBA 1.68433059977701 0.427 0.136 1.91252805800197e-171
IL1RN 1.62308597768549 0.658 0.316 1.44736840169875e-167
C15orf48 1.63563736818476 0.804 0.535 1.15006176511386e-156
TNF 1.49983990876771 0.462 0.168 3.03089234634647e-154
IL6 1.79857251786134 0.399 0.16 6.75454143011564e-108
CXCL1 1.46240657163808 0.471 0.232 7.74230829186934e-86
CXCL5 1.46555372779905 0.155 0.055 3.54242679039127e-40

Cluster 8

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
LYVE1 3.00980035050828 0.549 0.036 0
RNASE1 2.84428824560095 0.902 0.348 0
F13A1 2.64304236210123 0.764 0.165 0
SEPP1 2.4884400223409 0.977 0.315 0
FOLR2 2.48581061674403 0.785 0.199 0
DAB2 1.83309382520204 0.851 0.389 0
MAF 1.72421624862031 0.73 0.256 0
C1QA 1.62902442239404 0.995 0.576 0
STAB1 1.70544945823903 0.794 0.331 1.19408427122442e-296
SLC40A1 1.54131523198185 0.776 0.29 7.80899598706579e-282
PDK4 1.89180321746494 0.524 0.137 8.36000889067993e-273
PLTP 1.9614735505435 0.644 0.229 2.93049282801976e-271
MS4A4A 1.76769438505343 0.815 0.4 2.25605962058989e-270
LGMN 1.64580163678171 0.892 0.47 1.38583741581337e-269
GYPC 1.75082459665254 0.675 0.287 2.86828955928141e-237
CFD 1.94449277022172 0.826 0.452 3.90673687850081e-237
IGHA1 1.86668116768434 0.886 0.553 9.1426944683548e-199
BLVRB 1.56549617699416 0.783 0.479 5.29701126121696e-189
IGLC2 1.80549982048515 0.571 0.433 5.44056677303242e-34
IGJ 1.98667660876521 0.249 0.189 3.70354618281744e-07

Cluster 9

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
S100A8 3.86400642367713 0.975 0.32 0
S100A9 3.418516939398 0.998 0.555 0
S100A12 3.16918986826233 0.709 0.094 0
VCAN 2.38354507666053 0.826 0.195 0
FCN1 2.28345994960231 0.809 0.163 0
S100A4 1.37823694553424 0.995 0.855 9.06755890091952e-296
RP11-1143G9.4 1.79939120384678 0.808 0.441 6.30818520587839e-216
MCEMP1 1.37112922437203 0.422 0.101 2.18917850909095e-211
SERPINA1 1.28182933618262 0.825 0.46 4.1783655698855e-196
CSTA 1.4453381990737 0.733 0.395 3.06332990205453e-193
THBS1 1.53030433505317 0.512 0.18 2.6755715290077e-162
SERPINB2 1.55183135322234 0.225 0.039 3.9364810187414e-147
RETN 1.4775869332243 0.366 0.1 6.32516822923218e-146
CD55 1.33000180159996 0.621 0.313 7.60320502637013e-144
EREG 1.51819276043273 0.618 0.285 4.11444965061585e-130
TIMP1 1.33646622511715 0.894 0.751 8.37273116182719e-116
BCL2A1 1.51610309378775 0.766 0.511 3.41120413929798e-110
STXBP2 1.25133075669514 0.61 0.366 4.87151167683064e-101
IL1B 1.39747990394175 0.801 0.549 3.71011363099611e-91
CCL20 1.3164458422574 0.425 0.267 6.29395419248282e-35

Cluster 10

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
HSPA6 3.7515727665948 0.631 0.151 0
HSPA1B 3.28469594344835 0.914 0.385 0
HSPA1A 3.21453183959534 0.943 0.547 0
DNAJB1 3.05558054063206 0.868 0.461 0
HSP90AA1 2.81645855611093 0.98 0.868 0
HSPH1 2.76999426786797 0.791 0.314 0
BAG3 2.27363734457924 0.515 0.109 0
DNAJA4 1.76431356891228 0.417 0.093 1.69067322483919e-231
TIMP1 2.32955465762171 0.939 0.749 2.39009599920685e-205
ZFAND2A 2.0817179126993 0.485 0.146 9.4643258378658e-202
C15orf48 1.53661489520841 0.847 0.537 5.78343399235328e-155
HSPD1 2.00548032763401 0.695 0.433 2.16494971337868e-144
HSPB1 2.51599264479338 0.793 0.625 1.17866921434285e-143
HILPDA 1.43835122917152 0.192 0.035 4.85123359756674e-118
IL1RN 1.55798438753882 0.632 0.323 6.2235920951846e-113
LDHA 1.42538974200189 0.816 0.668 6.58597456230945e-111
SLC2A3 1.63701371976014 0.673 0.437 1.63778924613287e-101
HSPE1 1.65783917043009 0.737 0.601 6.45399899323325e-96
PLIN2 1.53184507282836 0.665 0.504 1.13964494318261e-67
IER5 1.47639939759908 0.474 0.3 4.86724073671858e-54

Cluster 11

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
MT1G 4.15546359146751 0.764 0.117 0
MT1H 3.63863457783693 0.536 0.038 0
MT1X 3.61780398805444 0.852 0.293 0
MT1E 2.64451998032724 0.635 0.125 0
MT1F 1.86902541536209 0.67 0.143 0
MT1M 1.63207384364685 0.337 0.019 0
MT2A 2.97479916736997 0.93 0.558 4.21480639331408e-295
CXCL5 2.7786424476311 0.307 0.049 8.24746123135054e-204
MMP1 2.54679645563807 0.318 0.07 8.10903958302446e-149
MMP14 1.0541333296872 0.641 0.29 2.53635882499741e-121
MMP12 2.48195294399062 0.482 0.186 2.8002392931692e-110
MMP9 1.6722462219336 0.534 0.244 2.36938562493272e-97
CXCL1 1.83782865983728 0.529 0.234 4.05088387110402e-92
IL7R 1.27772319766092 0.469 0.19 5.68404454647011e-92
SPP1 1.55418195243328 0.564 0.268 7.39207245145253e-89
CCL18 2.00571654247596 0.396 0.152 2.46886279174737e-80
CTSL 0.990991647432767 0.83 0.538 5.96372159230575e-76
MMP10 0.974709323364396 0.107 0.017 1.44471655751551e-65
MT-RNR2 1.07022883177232 0.311 0.203 4.44568099888193e-16
IGJ 1.00623587918517 0.304 0.187 1.94831379314333e-13

Cluster 12

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
CXCL10 3.60739983547289 0.574 0.083 0
CXCL11 1.89714419749236 0.261 0.017 0
APOBEC3A 1.88885963208222 0.481 0.067 0
GBP5 1.44190117402405 0.541 0.094 1.22694354632879e-293
GBP1 2.11721709317 0.736 0.206 3.29235250433534e-290
WARS 1.78799513503643 0.774 0.257 1.7371316776949e-241
IDO1 1.70104382014255 0.381 0.056 9.38512476464661e-229
IFITM3 1.9327056008677 0.946 0.647 3.50490379075428e-198
VAMP5 1.88469075175942 0.804 0.367 6.21069843350966e-186
FAM26F 1.68430251721287 0.843 0.434 7.08205485831612e-180
CXCL9 2.18054941483986 0.353 0.067 1.8826812105145e-163
PSME2 1.37076223192724 0.907 0.618 2.72869677070993e-150
LY6E 1.42173330741382 0.858 0.456 7.6023624232022e-144
ISG15 2.40179211901007 0.866 0.495 1.66024138576747e-138
ISG20 1.66276550812191 0.586 0.225 8.15766090782114e-118
PLAC8 1.45404647870427 0.495 0.171 8.30780943943467e-106
FCN1 1.34673947377562 0.524 0.186 2.55067064850362e-104
IFIT2 1.39001867404811 0.367 0.101 4.06117860622342e-100
IFI6 1.31256019259745 0.785 0.419 2.35378097875587e-99
CCL8 1.56479616559272 0.148 0.053 3.23662294929215e-21

Cluster 13

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
KIAA0101 2.62874182685379 0.899 0.04 0
UBE2C 2.1109547563605 0.658 0.025 0
CKS1B 2.03658292718395 0.859 0.144 0
TYMS 1.96407609386082 0.787 0.022 0
TK1 1.9020010215066 0.777 0.035 0
RRM2 1.71471581897336 0.656 0.011 0
CDK1 1.69578763016098 0.691 0.029 0
TOP2A 1.52967549192801 0.559 0.013 0
BIRC5 1.47120592000047 0.634 0.018 0
STMN1 2.69588414294924 0.963 0.31 1.53252517595174e-283
PCNA 1.73388682575228 0.713 0.125 2.21366848389165e-281
PTTG1 1.52869056252037 0.621 0.101 4.96363255363338e-246
H2AFZ 2.44763168595359 0.985 0.674 1.13470766972969e-227
TUBB 2.38776634537695 0.975 0.553 3.81819720211335e-217
HIST1H4C 2.70249446976419 0.72 0.176 5.714456212613e-207
TUBA1B 2.33152527650433 0.993 0.703 1.5557283191526e-186
HMGB2 2.19926194829924 0.879 0.342 3.05582049435306e-180
DUT 1.75490670977656 0.847 0.302 2.12427447069767e-177
HMGB1 1.67188925766611 0.978 0.732 3.94838436198592e-168
HMGN2 2.09745388323538 0.958 0.598 1.00693457805349e-162

Cluster 14

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
GZMB 6.10410922393259 0.976 0.035 0
JCHAIN 3.55283515398217 0.929 0.207 0
C12orf75 3.32507430261117 0.926 0.077 0
TSPAN13 3.25006751912504 0.917 0.04 0
IRF7 3.13429636174064 0.944 0.203 0
PLAC8 3.04332520222834 0.973 0.167 0
LDLRAD4 3.02059532475018 0.826 0.156 0
SOX4 2.99052975005476 0.799 0.117 0
IRF4 2.94604814203542 0.882 0.038 0
LILRA4 2.69527075069921 0.829 0.015 0
CLIC3 2.50570993002132 0.681 0.014 0
PPP1R14B 2.47189511946529 0.82 0.143 0
PLD4 2.3527511658116 0.782 0.092 0
TCF4 2.3698252937488 0.873 0.186 1.72927852347683e-290
ITM2C 2.50451799074017 0.894 0.193 4.62870525715319e-289
PTGDS 4.1339644752249 0.419 0.034 7.06536194972568e-283
NR3C1 2.83256822375213 0.844 0.226 8.57164206011153e-228
LTB 3.17663597370114 0.693 0.133 1.83648409535186e-223
SEC61B 2.41014012728942 0.994 0.709 2.81014311480739e-194
GPR183 2.43965851490972 0.973 0.599 5.87903976931235e-143

Cluster 15

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
CLEC9A 2.77997486261577 0.929 0.03 0
IDO1 2.67193914584395 0.904 0.059 0
CTD-2319I12.1 2.15012201925783 0.503 0.01 0
DNASE1L3 2.713319055935 0.99 0.203 1.64392877115581e-189
LGALS2 2.66457096351305 0.985 0.272 3.39772540837311e-164
CPNE3 1.74570328009884 0.741 0.139 3.86791857472418e-147
CPVL 3.04584394107789 0.99 0.447 2.82553352192995e-133
CST7 1.63011401206141 0.706 0.133 1.89294849103609e-125
SNX3 2.42528769795443 0.99 0.727 1.49959918196139e-114
C1orf54 2.10567624007449 0.904 0.309 1.04557110309382e-113
HLA-DQB2 1.6105580416628 0.629 0.114 5.77673370235688e-111
HLA-DPB1 2.07742694370342 1 0.858 9.50601111534257e-108
CD74 1.87224829996122 1 0.923 9.247292744524e-103
LSP1 1.90871977303821 0.98 0.505 9.35504114921089e-102
IRF8 1.93301798274266 0.883 0.325 3.32451666993112e-100
HLA-DPA1 1.84256665502316 1 0.852 1.34000612977194e-94
RGCC 2.24806517920019 0.924 0.363 1.73066002213273e-94
CST3 2.27143730347261 1 0.923 5.187475035683e-94
S100B 2.23245358880881 0.579 0.124 2.01226222110887e-88
HLA-DRB5 1.73537409351612 0.898 0.584 3.53214999466537e-37

Cluster 16

Gene Average Log2FC % Expressed in cluster % Expressed others p-value adjusted
CD3D 2.34218444471666 0.885 0.048 0
TRAC 2.27479803881656 0.842 0.04 0
KLRB1 2.19396936760469 0.585 0.029 0
TRBC2 1.98941189235428 0.721 0.038 0
CD7 1.8042969646119 0.689 0.043 0
TRBC1 1.71331415371237 0.508 0.02 0
CD2 1.69764595692081 0.721 0.035 0
CD3E 1.69722027017622 0.743 0.019 0
SPOCK2 1.23569976821992 0.59 0.015 0
CD3G 1.12767373869643 0.53 0.01 0
GZMA 1.79304838546148 0.393 0.026 7.48172109696482e-186
IL32 2.75042399572396 0.929 0.194 1.4312803055647e-172
FYN 1.04059412832194 0.563 0.059 2.89134265407672e-163
LTB 1.98386604875238 0.765 0.137 4.75857000942829e-137
TNFRSF18 1.11061565363727 0.481 0.057 3.44931945242171e-124
TNFRSF4 1.38676836234314 0.432 0.066 3.35883837157224e-82
CCL5 1.77816353297376 0.53 0.136 1.64690336285452e-54
GNLY 1.4219130658959 0.23 0.031 2.78651969756424e-46
DUSP4 1.01162603015283 0.557 0.178 1.92175491874413e-38
NKG7 1.12679974533241 0.355 0.116 9.37944342369909e-20

First annotations

Clusters Annotation Clusters Annotation
0 Anti-inflammatory mono/macro 9 Pro-inflammatory mono/macro
1 Pro-inflammatory mono/macro 10 Pro-inflammatory mono/macro
2 Anti-inflammatory mono/macro 11 Anti-inflammatory mono/macro
3 Anti-inflammatory mono/macro 12 Pro-inflammatory mono/macro
4 cDCs 13 ??
5 Mast cells 14 pDCs
6 Anti-inflammatory mono/macro 15 ??
7 Pro-inflammatory mono/macro 16 ??
8 Anti-inflammatory mono/macro

Hierarchical Clustering of Myeloid Clusters